MENTHONE: AN OVERVIEW OF THEIR PHARMACOLOGICAL IMPORTANCE AND NOVEL DERIVATIVES
Abstract
In the world of medical herbs, a highly valued member of the Lamiaceae family, is peppermint (Mentha piperita),. This review aims to fill this gap by providing a comprehensive examination of peppermint, encompassing its botanical characteristics, traditional and local medicinal uses, chemical constituents, and pharmacological activities and novel derivatives of menthone. Peppermint has been revered for centuries for its wide array of medicinal properties, ranging from its ability to alleviate digestive discomfort to its antimicrobial and analgesic effects. This paper synthesizes up-to-date information on the pharmacognosy and pharmacology of Mentha piperita, highlighting its diverse therapeutic potentials. By consolidating research findings from various studies, this review serves as a valuable reference for researchers seeking to explore the multifaceted benefits of peppermint in pharmaceutical and nutraceutical applications. From its essential oil to its various extracts, the pharmacological activities of peppermint, including its anti-inflammatory, antioxidant, and antispasmodic properties, are thoroughly elucidated. Furthermore, this review discusses the potential mechanisms underlying peppermint's pharmacological effects, and preparation on various novel derivatives of menthone. Overall, this paper provides insights into the Pharmacognostic and pharmacological aspects of peppermint, paving the way for further research and development of novel therapeutic interventions derived from this remarkable plant.
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