A PROSPECTIVE OBSERVATIONAL STUDY ON THE PREVALENCE OF DYSLIPIDEMIA AND CARDIOVASCULAR COMPLICATIONS IN HYPOTHYROID PATIENTS

Prevalence study on dyslipidemia and cardiovascular complications in hypothyroid patients

  • Raghavendra Kumar Gunda Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • Shaikh Mulla Mobin Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • MN Priya Department of Endocrinology, SPS Endocrine Centre, Palnadu, Andhra Pradesh, India.
  • JNS Kumar Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • A Rajesh Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • J Tejaswini Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • P Radhika Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
  • SK Azaruddin Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.

Abstract

Objective: The main objective of current study was to assess the prevalence of dyslipidemia and cardiovascular complications in Hypothyroid patients.


Methods: In this prospective observational study, 110 subjects have been participated. ASCVD scale is used which assess the next 10years cardiovacular risk of a patient. ASCVD score categorizes into low, intermediate, borderline and high. Hypothyroid patients are assessed with lipid profile followed by ASCVD scale.


Results:  ASCVD risk category distribution highlights a higher percentage in the low-risk category (71.82%). The study also reveals a strong association between hypothyroidism and hyperlipidemia, with the majority of patients having ideal hyperlipidemia levels (89%). Comorbidities such as hypertension and type 2 diabetes mellitus are prevalent, with a significant portion having no comorbidities (50.9%). Family history analysis shows a majority without a family history of hypothyroidism (84.5%).


Conclusion: From our study we concluded that despite the high prevalence of comorbidities, a substantial proportion of patients exhibited ideal lipid profiles, emphasizing the need for targeted interventions addressing modifiable risk factors. Family history and ASCVD risk assessment provide valuable insights into risk stratification and personalized treatment approaches. Overall, these findings underscore the importance of multidisciplinary approaches integrating endocrinology, cardiology, and lifestyle interventions in optimizing outcomes for hypothyroid patients at risk of cardiovascular complications.

Keywords: Hypothyroidism, Dyslipidemia, ASCVD Risk score, Cardiovascular complications, Levothyroxin

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How to Cite
Gunda, R., S. Mobin, M. Priya, J. Kumar, A. Rajesh, J. Tejaswini, P. Radhika, and S. Azaruddin. “A PROSPECTIVE OBSERVATIONAL STUDY ON THE PREVALENCE OF DYSLIPIDEMIA AND CARDIOVASCULAR COMPLICATIONS IN HYPOTHYROID PATIENTS”. Journal of Applied Pharmaceutical Sciences and Research, Vol. 7, no. 1, May 2024, pp. 55-59, doi:10.31069/japsr.v7i1.10.
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Research Articles

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