A PROSPECTIVE OBSERVATIONAL STUDY ON THE IMPACT OF TRIPLE THERAPY ALONE OR IN COMBINATION WITH PROBIOTICS TO IMPROVE THE QUALITY OF LIFE IN H. PYLORI INFECTED PATIENTS

  • Raghavendra Kumar Gunda Narasaraopeta Institute of Pharmaceutical Sciences
  • Swetha A Prthima Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Palnadu, Andhra Pradesh, India.
DOI https://doi.org/10.31069/japsr.v7i2.06

Abstract

Objective: The main objective of the current study was to assess the impact of triple therapy alone or in combination with probiotics to improve the quality of life in H. pylori-infected patients.
Methods: In this prospective observational study, 120 subjects participated. Quality of life instrument for chronic diseases-peptic ulcer (QLICD-PU) scale, which consists of a set of questions, was used to assess the patient’s symptom severity. Based on the QLICD-PU scale, the subjects were divided into categories, i.e., mild, moderate, severe and prescribed with H. pylori- kit in combination with probiotics and reviewed the patient efficacy.
Results: From the analysis of severity score assessed using the QLICD-PU scale, on the first day of the visit, patients with severity were found to be 87% (n = 104), moderate was 13% (n = 16), and mild were 0, and after two follow-ups over a period of 6 months the patients with symptom severity were 0, moderate was 2.5% (n = 95), mild was 77.5% (n = 22) and completely cured subjects were 20% (n = 24).
Conclusion: From our study, we concluded that H. pylori kit shows more effect when prescribed in combination with probiotics than when prescribed alone, as most of the patients prescribed with a combination of H. pylori kit with probiotics attain more effects than the patients prescribed with H. pylori kit alone.

Keywords: Helicobacter pylori Infection, QLICD-PU, H.pylori kit, Probiotics, Combination Therapy

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How to Cite
Gunda, R., and S. Prthima. “A PROSPECTIVE OBSERVATIONAL STUDY ON THE IMPACT OF TRIPLE THERAPY ALONE OR IN COMBINATION WITH PROBIOTICS TO IMPROVE THE QUALITY OF LIFE IN H. PYLORI INFECTED PATIENTS”. Journal of Applied Pharmaceutical Sciences and Research, Vol. 7, no. 2, 1, pp. 34-39, doi:10.31069/japsr.v7i2.06.
Issue
Vol 7 No 2 (2024): Volume 7, Issue 2, 2024
Section
Research Articles

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