A PROSPECTIVE OBSERVATIONAL STUDY AND COMPARATIVE EFFICACY OF TOPICAL BENZOYL PEROXIDE AND MINOCYCLINE GEL WITH AND WITHOUT ADDED CHEMICAL PEEL IN ACNE TREATMENT

Effect of Chemical peel on the treatment of Acne vulgaris

  • Dr R.V.S.S LathaSri Narasaraopeta Institute of Pharmaceutical Sciences, Assistant Professor, Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India - 522601.
  • Raghavendra Kumar Gunda Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
  • Dr J.N. Suresh Kumar Professor cum Principal, Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
  • K Sruthi Dermatologist, and Aesthetic Surgeon, Dr. Kondapalli Hospitals and Sruthi Skin Clinic, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India - 522601.
  • N Rama Krishna Consultant Dermatologist, Manasa Skin Care Clinic, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India - 522601.
  • Ch Surendra Reddy Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
  • KL Prasanna Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
  • P Kalyan Kumar Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
  • V Bhavana Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.
DOI https://doi.org/10.31069/japsr.v7i1.08

Abstract

Objective: This prospective observational study aims to evaluate effectiveness of combination of topical benzoyl peroxide and minocycline gel comparing it with and without added chemical peel in acne vulgaris treatment


Methods: In This study we have observed the effectiveness of two different treatment regimens in acne treatment. Based on the GAGS Scale the severity index of subjects were observed. A cohort of 110 young and adult population are included in our study.


Results: A study on Acne vulgaris (110 cases, 6 months) revealed a higher prevalence among females (70.9%). Severity at visit: severe (65.4%), moderate (24.5%), very severe (10.1%). Follow-ups showed a decrease in severe cases and an increase in mild. No initial counselling on food limitations was provided. Males comprised 29.1% of cases. Further analysis may elucidate treatment efficacy and the potential impact of lifestyle factors on acne management.


Conclusion: This study compares combining topical benzoyl peroxide and minocycline gel alone versus with chemical peel for acne treatment. Chemical peel adjunct shows enhanced efficacy, lower recurrence, and scar reduction. Female predominance noted among 110 patients. Regular follow-ups and standardized acne scoring recommended. Physicians should be educated on benefits of combination therapy. Result is better clinical clearance with chemical peel addition.

Keywords: Acne vulgaris, Chemical peel, Minocycline gel, Benzoyl peroxide, Lifestyle, Efficacy

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Author Biographies

Dr R.V.S.S LathaSri, Narasaraopeta Institute of Pharmaceutical Sciences, Assistant Professor, Department of Pharmacy Practice, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India - 522601.

Dr. R.V.S.S. lathasri Pharm.D., 

Assistant Professor, Department of Pharmacy Practice,

Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet,

Palnadu (Dt), Andhra Pradesh, India - 522601.

E-mail: sathyalathasri95@gmail.com,

Mob: +91-7207298829.

Dr J.N. Suresh Kumar, Professor cum Principal, Department of Pharmaceutics, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu (Dt), Andhra Pradesh, India-522601.

Dr. J.N. Suresh Kumar,

Professor cum Principal, Department of Pharmaceutics,

Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopet,

Palnadu (Dt), Andhra Pradesh, India-522601.

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How to Cite
LathaSri, D., R. Gunda, D. Kumar, K. Sruthi, N. Krishna, C. Reddy, K. Prasanna, P. Kalyan Kumar, and V. Bhavana. “A PROSPECTIVE OBSERVATIONAL STUDY AND COMPARATIVE EFFICACY OF TOPICAL BENZOYL PEROXIDE AND MINOCYCLINE GEL WITH AND WITHOUT ADDED CHEMICAL PEEL IN ACNE TREATMENT”. Journal of Applied Pharmaceutical Sciences and Research, Vol. 7, no. 1, May 2024, pp. 46-49, doi:10.31069/japsr.v7i1.08.
Issue
Vol 7 No 1 (2024): Volume 7, Issue 1, 2024
Section
Research Articles

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