TREATMENT OF HELICOBACTER PYLORI INFECTION: A REVIEW
Abstract
Helicobacter pylori is a particular bacterium that has evolved to survive in the acidic environment of the human stomach. Currently, no single antibiotic can treat the infection, so multiple medications are needed for treatment. Two antibiotics given more than a few times each day for seven to fourteen days, together with acid-suppressing medications, are the standard recommended treatments. The purpose of this review was to conclude the treatment of H.pylori infection. Without standard triple therapy, which consists of amoxicillin, clarithromycin, and PPI for the first five days, followed by PPI, clarithromycin, and tinidazole for the final five days, is the most frequently used course of treatment for clarithromycin-resistant H. pylori infections. Moreover, One of the first therapeutic regimens for the removal of H. pylori infection included bismuth-based therapy (bismuth salts, metronidazole, and tetracycline, each four times daily for two weeks with PPI), but the number of tablets taken daily and the associated mild side effects can have a negative effect on tolerance and compliance. Therefore, it is usually kept as a second-line treatment. Finally, rescue therapy (PPIs, Levofloxacin, and amoxicillin twice daily for 10 days) is a recently suggested treatment for H. pylori infection. This combination can cure about 80% of patients with H. pylori infection who have already tried one or more earlier treatments but failed.
Downloads
All the articles published in JAPSR are distributed under a creative commons license (CC BY-NC-SA 4.0)
Under this license, you are free to:
- Share- copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt- remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms.
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes .
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Copyright policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
Licensing policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
