NOVEL FRONTIERS IN BUCCAL PATCHES: A RECENT UPDATE
Abstract
Buccal route found to be more suitable for the delivery of pharmaceutical agents using mucoadhesive polymers due to presence of relatively
static and smooth surface on which various mucoadhesive dosage forms can be placed. Different dosage forms like films, tablets, gels, ointments
and patches can be used for delivery of drug across the buccal mucosa. The drugs may be suitable candidates to be delivered via the oral cavity
which are having short biological half-life, poor solubility and permeability, susceptible to enzymatic degradation and for achieving sustain
release effect. The mucoadhesive drug delivery provides greater absorption and enhanced bioavailability of dosage forms due to the large surface
area and higher blood flow in the mucosal cavities. The delivery across the mucus membrane provides various advantages over other drug
delivery routes i.e., overcome the hepatic first pass metabolism as well as the degradation of drugs by various gastrointestinal enzymes as well as
intestinal flora.
Downloads
All the articles published in JAPSR are distributed under a creative commons license (CC BY-NC-SA 4.0)
Under this license, you are free to:
- Share- copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt- remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms.
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes .
- ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Copyright policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
Licensing policy
The journal allows the author(s) to hold the copyright of their work. That means the authors do not need to transfer the copyright of their work to the journal. However, the authors grant JAPSR a license to publish the article and identify itself as the original publisher.
