THE POTENTIAL ADVANTAGES OF LIPID NANOPARTICLES IN TREATMENT OF ACNE

  • Vipul Ajit Sansare Department of Pharmaceutics, Indira Institute of Pharmacy, Sadavali
  • Abhijeet Mohan Kanavaje Department of Pharmaceutics, Indira Institute of Pharmacy, Sadavali

Abstract

Acne is a disfiguring disorder of the skin with significant cosmetic morbidity that may lead to serious psychological and social dysfunction. The skin disease comes in two forms. The most well-known form is Acne vulgaris (referred to as acne), which mostly manifests in teens but may continue into the early 20s. The second form is called Acne rosacea (referred to as rosacea) and mostly affects 30- to 60-year-olds. The two forms, despite sharing a common prefix, are quite unrelated in their respective pathophysiology, have different approaches to treatment and hence are considered two separate conditions. The conventional drug delivery system is efficient in the management of acne but poor patient compliance and adverse effects limit its efficacy. Lipid nanoparticles are novel nano lipid carriers made from biocompatible lipid which reduces toxicity; improve physical stability, skin hydration, and film formation. Furthermore, lipid nanoparticles protect the encapsulated drug from degradation. Thus current review focused on the potential use of lipid nanoparticles for the management of acne.

Keywords: Acne, Rosacea, Solid lipid nanoparticles, Topical drug delievry, Nanolipids, Acne vulgaris

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How to Cite
Sansare, V., and A. Kanavaje. “THE POTENTIAL ADVANTAGES OF LIPID NANOPARTICLES IN TREATMENT OF ACNE”. Journal of Applied Pharmaceutical Sciences and Research, Vol. 2, no. 3, Oct. 2019, pp. 6-13, doi:10.31069/japsr.v2i3.2.
Section
Review Articles