IMPORTANCE OF HERBAL DRUG FOR NEW DRUG DEVELOPMENT
Drug discovery leading to robust and viable lead candidates’ remains a challenging scientific task, which is the transition from a screening hit to a drug candidate, requires expertise and experience. Natural products and their derivatives have been recognized for many years as a source of therapeutic agents and of structural diversity. However, in addition to their chemical structure diversity and their biodiversity, the development of new technologies has revolutionized the screening of natural products in discovering new drugs.
2. Patel P, Potti H. Impact of the Traditional Herbal Medicinal Products Directive (THMPD) - The New Challenge for Global Ayurveda. Accessed: 15 September 2018. [Online]. Available: http://iafngo.org/pdf/WAC%20SPEECH%20BY%20DR.%20VIDHI%20BAPNA%20%28No.%2017%29.pdf.
3. European Medicines Evaluation Agency (EMEA). Committee on Herbal Medicinal Products (HMPC), EMA/HMPC/345132/2010 Rev.21Corr, 7 June; 2013. Accessed: 15 September 2018. [Online]. Available: http://fliphtml5.com/qnjc/xatt/basic/.
4. World Health Organization, Good manufacturing practices: Supplementary guidelines for manufacture of herbal medicinal products. WHO Expert Committee on Specifications for Pharmaceutical Preparations. Thirty-fourth report. World Health Organization. Geneva, Switzerland: WHO Press, 1996, Annex 8, no. 863, 134–139.
5. Verpoorte R, Mukherjee PK, GMP for Botanicals. Accessed: 15 September 2018. [Online]. Available: http://businesshorizons.com/, 2003.
6. Straus S. Herbal medicines – What’s in the bottle?. New England Journal of Medicine. 2002; 347: 1997–1998.
7. Pillai NR, Antidiarrheal activity of Punica granatum in experimental animals. International Journal of Pharmacognosy. 1992; 30: 201–204.
8. Ministry of Ayush, Government of India, The Ayurvedic Pharmacopoeia of India, Part-1, vol. IX, New Delhi: Pharmacopoeia Commission for Indian Medicine & Homoeopathy, 2016.
9. Vaidya RA, Ayurvedic pharmacoepidemiology – a proposed new discipline. Journal of the Association of Physicians of India. 2003; 51: 528.
10. Kokate CK, Khandelwal KR, Pawer AP, Gokhale SB. Practical Pharmacognosy, 3rd ed., Pune: Nirali Prakashan, 1995, 137.
11. Gupta AK, Tandon N, Sharma M. Quality Standards of Indian Medicinal Plants. Vol. 7, New Delhi: Indian Council of Medical Research, 2008: 331-339.
12. Pandey MK, Singh GN, Sharma R, Snehlata. Standardization of Yakrit Plihantak Churna: An Ayurvedic Polyherbal formulation. International Journal of Pharmaceutical Science and Research. 2012; 3(1):171-176.
13. Swamy P, Mulla SK, Preliminary Pharmacognostical and Phytochemical Evaluation of Portulaca quadrifida Linn. International Journal of Pharmaceutical Technology and Research. 2010; 2(3):1699-1702.
14. Chanderachud S, Khatri SP, Jain A, Vaidya A. Pharmacognostic and Phyto chemical Investigations of the Leaves of Zizyphus xylopyrus (Retz) Willd. International Journal of Pharmacy and Pharmaceutical Sciences. 2011; 3(2):122-125.
15. World Health Organization, Quality Control Methods for Medicinal Plant Materials, Updated ed. Geneva, Switzerland: WHO Press, 2011.
16. Kirtikar KR, Basu BD, Indian Medicinal Plants, Vol. III. Dehradun: Bishen Singh Mahendra Pal Singh, 2003: 1655-1656.
17. World Health Organization, Legal status of traditional medicine and complementary/alternative medicine: a worldwide review. Geneva, Switzerland: WHO Press, 2001.